1.
Chinese Journal of Pharmacology and Toxicology
;
(6): 597-606, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-613968
ABSTRACT
Endogenous formaldehyde is generated in the human body.When the system of endogenous formaldehyde generation with scavengation is damaged,excess accumulation of endogenous formaldehyde induces vascular endothelial injury,atherosclerosis,myocardial damage and neurodegenerative diseases.Studies show that endogenous formaldehyde is one of the key factors during the process of cardiovascular and cerebrovascular diseases.Moreover,polyphenols are used as capture agents of endogenous formaldehyde to prevent and treat cardiovascular and cerebrovascular diseases.